The iLas Pulse system is a unique tool for Subcellular Nano-surgery and Nano-irradiation combined with FRAP/Photoactivation. Coupled to a microscope, it addresses a wide variety of bio-physical applications.
Precise focusing of pulsed laser light in real time enables non-invasive manipulation of the structural machinery of living cells with several-hundred nanometer resolution.
Banner Credits: RPEI Cells transfected with lifeact-GFP. Dr Timothée Vignaud, Dr Laurent Blanchoin Team at CEA Grenoble, France. Laser ablation at 355 nm permits visualization of relaxation of a single actin stress fiber after targeted ablation. Central part of the images was enhanced for better visualization.